Emphatic victory over Tottenham Hotspur in first leg sees German club lead pack in last 16
Borussia Dortmund appear closest of the Europa League's final 16 to qualification to the quarter-finals after the German side beat Tottenham Hotspur 3-0 on Thursday night.
A first-half goal from Pierre-Emerick Aubameyang and two from Marco Reus in the second-half secured a definitive victory against the north London club in the first leg of the round.
In Istanbul, Fenerbahce triumphed over Portugal's Braga through Mehmet Topal's late shot - the only goal of the closely fought match. The game was the Super Lig leader's 12th straight home win.
A clash between two former European champions, Liverpool and Manchester United, saw Liverpool win 2-0 in the first European clash between the rivals. Elsehwhere, Shakhtar Donetsk triumphed over Belgian side Anderlecht although the visitors got a valuable away goal in Ukraine.
Second leg matches will be played on March 17.
Shakhtar Donetsk 3-1 Anderlecht
Basel 0-0 Sevilla
Borussia Dortmund 3-0 Tottenham Hotspur
Fenerbahce 1-0 Braga
Villarreal 2-0 Bayer Leverkusen
Athletic Bilbao 1-0 Valencia
Liverpool 2-0 Manchester United
Sparta Prague 1-1 Lazio